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The Non-Malignant Channel:
Sickle Cell Disease

Explore the latest updates and expert interviews

The Sickle Cell Disease Channel on VJHemOnc is an independent medical education platform, supported with funding from Agios (Gold). Supporters have no influence on the production of content. The levels of sponsorship listed are reflective of the amount of funding given.

Latest videos Conferences Topics Sessions Features Podcasts Expert Editorial Board

Welcome to The Sickle Cell Disease (SCD) Channel.

VJHemOnc brings you the latest updates in SCD directly from esteemed experts around the world. The SCD Channel brings you video interviews, podcasts, features, and roundtable discussions. As well as updates in novel treatment approaches, The SCD Channel covers advances in gene therapies for SCD, updates from ongoing clinical trials, and more.

Conferences

EHA 2025
ESH Erythro 2025
ASH 2024
ASCAT 2024
EHA 2024
BSH 2024
1:26
Opportunities to combine mitapivat with other therapies in clinical trials
Maria Domenica Cappellini • 15 Jun 2025
2:41
Exploring mitapivat in thalassemia & SCD: the potential upcoming approval of the agent
Maria Domenica Cappellini • 15 Jun 2025
1:22
Navigating SCD together: the importance of patient and physician collaboration
Caterina Minniti • 14 Jun 2025
1:31
The potential of the novel EED inhibitor pociredir in sickle cell disease
Caterina Minniti • 14 Jun 2025
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1:28
The growing role of gene editing and gene therapy in SCD & important practical considerations
Sara El Hoss • 21 Mar 2025
1:28
Repurposing drugs in sickle cell disease: lessons learned from hydroxyurea
Sara El Hoss • 21 Mar 2025
2:21
The impact of ineffective erythropoiesis in hemoglobinopathies & underlying mechanisms
Sara El Hoss • 21 Mar 2025
2:03
Potential therapeutic avenues being explored to target inflammation in thalassemia & SCD
Francesca Vinchi • 21 Mar 2025
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2:26
Preventing and managing vaso-occlusive crises in SCD: the importance of early intervention
Sanne Lugthart • 5 Dec 2024
4:15
A virtual hospital approach in SCD: remote biometric, QoL, and hospitalization monitoring
Sanne Lugthart • 5 Dec 2024
2:31
Comparing experiences of patients with SCD in developed and developing countries: UK versus India
Sanne Lugthart • 5 Dec 2024
2:01
Enhanced AI-driven prediction of VOCs in patients with SCD
Sanne Lugthart • 5 Dec 2024
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2:47
Sickle cell retinopathy: prevalence and managing patients with this complication
Christiana Dinah • 2 Oct 2024
2:07
Important considerations when managing a pediatric patient with sickle cell disease
David Rees • 3 Oct 2024
3:01
The feasibility of hydroxyurea mobile directly observed therapy in patients with SCD in SSA
Enrico Novelli • 30 Sep 2024
2:21
Hydroxyurea and follicular density in females with SCD, and the importance of fertility preservation
Jean-Hugues Dalle • 3 Oct 2024
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0:39
Factors to consider when selecting patients with SCD for alloSCT
Elisabeth Dovern • 15 Jun 2024
0:51
Changes in physical, mental, and social health of adults with SCD following alloSCT
Elisabeth Dovern • 15 Jun 2024
1:01
Preconditioning prior to non-myeloablative matched sibling donor HSCT in patients with SCD
Elisabeth Dovern • 15 Jun 2024
1:33
An update on the Phase I/II RUBY trial of reni-cel gene therapy in patients with severe SCD
Rabi Hanna • 16 Jun 2024
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2:27
Optimizing the delivery of care for patients with hemoglobinopathies in the UK
Farrukh Shah • 30 Apr 2024
1:12
Working towards health equity in sickle cell disease: addressing discrimination and bias
Marsha Treadwell • 29 Apr 2024
3:47
The modeling of HbS dynamics following red cell exchange transfusion to improve patient care
Richard Salisbury • 28 Apr 2024
2:46
Morbidity and mortality data from the UK National Haemoglobinopathy Registry
Farrukh Shah • 30 Apr 2024
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Topics

Treatment
Disease biology
Trial Updates
Transplantation
Immuno-oncology
6:48
The role of inflammation in SCD pathophysiology and potential avenues for targeting it
Subarna Chakravorty • 3 Nov 2025
2:05
Harmonizing sickle cell disease guidelines in the EU
Minke Rab • 13 Oct 2025
1:52
Managing sickle cell disease in pregnancy: utilizing prophylactic transfusions in this setting
Sheinei Alan • 16 Oct 2025
3:04
Pociredir in sickle cell disease: mechanism of action and Phase Ib trial design
Sheinei Alan • 16 Oct 2025
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6:48
The role of inflammation in SCD pathophysiology and potential avenues for targeting it
Subarna Chakravorty • 3 Nov 2025
3:03
Examining the early-life clinical and hematological profiles of patients with sickle cell disease
Siana Nkya • 20 Oct 2025
4:41
What is HbSC disease, and how does it differ from HbSS disease in pathophysiology and presentation?
Minke Rab • 13 Oct 2025
3:56
Pharmacogenomics in sickle cell disease: factors influencing treatment response to hydroxurea
Siana Nkya • 20 Oct 2025
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2:20
Updated results of RUBY: the positive effects of reni-cel gene therapy in patients with severe SCD
Rabi Hanna • 9 Dec 2024
3:03
Results of the Phase II HIBISCUS trial investigating etavopivat in sickle cell disease
Sophia Delicou • 29 Nov 2024
1:33
An update on the Phase I/II RUBY trial of reni-cel gene therapy in patients with severe SCD
Rabi Hanna • 16 Jun 2024
0:37
Inhibiting HbS polymerization to treat SCD: insights from a Phase II trial
Santosh Saraf • 8 Dec 2023
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10:55
Transplantation and gene therapy in SCD and thalassemia: donor types and indications
Subarna Chakravorty • 3 Nov 2025
3:26
Selecting between treatment options for patients with sickle cell disease in the UK
Samah Babiker • 17 Oct 2025
1:58
The role of palliative care in patients with sickle cell disease undergoing SCT or gene therapy
Akshay Sharma • 9 Apr 2025
4:08
The main benefits and challenges of gene therapy for sickle cell disease
Akshay Sharma • 9 Apr 2025
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5:14
Advances in the treatment of SCD & thalassemia: luspatercept, mitapivat, gene therapy, and more
Maria Domenica Cappellini • 18 Mar 2025
1:58
Manipulating immune targeting of solid tumors with gene therapy
Akshat Jain • 8 Dec 2023
0:45
Current landscape of treatment for SCD: an update from ASH 2023
Santosh Saraf • 8 Dec 2023
1:12
An update in cellular therapies: gene editing for SCD and immunotherapies for MM
Sergio Giralt • 8 Dec 2023
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The Sickle Cell Disease Channel on VJHemOnc is an independent medical education platform, supported with funding from Agios (Gold). Supporters have no influence on the production of content. The levels of sponsorship listed are reflective of the amount of funding given.

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The content of VJHemOnc is intended for healthcare professionals