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IMS 2022 | Relevance of panobinostat-bortezomib-dexamethasone in R/R myeloma in the era of novel agents

Karthik Ramasamy, MBBS, MRCP, FRCPath, PhD, Oxford University Hospitals NHS Foundation Trust, Oxford, UK, gives an overview of the results of a real-world study examining the role of the combination of panobinostat, bortezomib, and dexamethasone in patients with relapsed/refractory (R/R) multiple myeloma in 2022. The study found that this combination led to significant clinical responses in a small population. According to Dr Ramasamy, this combination should be considered in patients who have shown good prior responses with bortezomib, good bone marrow reserve, and without prior neuropathy. This interview took place at the 19th International Myeloma Society Meeting (IMS) held in Los Angeles, CA.

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