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The 4th International Workshop on Myelodysplastic Syndromes & Myeloproliferative Neoplasms (iwMDS & iwMPN) took place on 2–4 October 2026, in Washington DC. At this event, the world’s leading clinical researchers in MDS & MPNs shared their perspectives on how to place the evolving understanding of these hematological malignancies in a clinical context to optimize clinical care.

iwMDS 2026

The 4th International Workshop on MDS & MPNs
01–04 October 2026 | Washington DC, USA

iwMDS 2026

The 4th International Workshop on MDS & MPNs
01–04 October 2026 | Washington DC, USA
The 4th International Workshop on Myelodysplastic Syndromes & Myeloproliferative Neoplasms (iwMDS & iwMPN) took place on 2–4 October 2026, in Washington DC. At this event, the world’s leading clinical researchers in MDS & MPNs shared their perspectives on how to place the evolving understanding of these hematological malignancies in a clinical context to optimize clinical care.

Keynote talk

Amer Zeidan
icMDS: progress and future directions
Amer Zeidan Yale University School of Medicine and Yale Cancer Center, New Haven, CT, United States
Coming soon

What is the current best practice in higher-risk MDS?

Yasmin Abaza
Venetoclax still has a role in higher-risk MDS: Yes
Yasmin Abaza Northwestern University, Chicago, IL, United States
Coming soon
Mikkael  Sekeres
Venetoclax still has a role in higher-risk MDS: No
Mikkael Sekeres Sylvester Comprehensive Cancer Center, Miami, FL, United States
Coming soon
Yazan Madanat
How I will treat higher-risk MDS in 2027
Yazan Madanat UT Southwestern Medical Center, Dallas, TX, United States
Coming soon
Amer Zeidan
Evolving antibodies in management of higher risk MDS
Amer Zeidan Yale University School of Medicine and Yale Cancer Center, New Haven, CT, United States
Coming soon
Maximilian Stahl
Lessons learned from a decade of higher-risk MDS trials
Maximilian Stahl Yale Cancer Center, New Haven, CT, United States
Coming soon
Klaus  Metzeler
Strategies for bridging HR-MDS patients to allogeneic transplantation
Klaus Metzeler University of Leipzig, Leipzig, Germany
Coming soon

From CHIP to MDS

Michael Savona
Using the CHIVE registry to better understand risk of CH
Michael Savona Vanderbilt University, Nashville, TN, United States
Coming soon
Uma Borate
How to design studies for CCUS and CHIP
Uma Borate Ohio State University, Columbus, OH, United States
Coming soon

Diagnosis, classification and prognostication in MDS and MDS/MPN

Arjan van de Loosdrecht
Incorporation of flow cytometry in diagnosis and classification of MDS
Arjan van de Loosdrecht Amsterdam UMC, Amsterdam, Netherlands
Coming soon
Tariq Kewan
Prognostication in TP53-mutated MDS – is there any “good” subtype?
Tariq Kewan Yale School of Medicine, New Haven, CT, United States
Coming soon
Matteo Della Porta
How can AI help in MDS prognostication and management?
Matteo Della Porta Humanitas Research Hospital, Milan, Italy
Coming soon
Fabio Efficace
Development of the icMDS-PRO score
Fabio Efficace Italian Group for Adult Hematologic Diseases (GIMEMA), Rome, IL, Italy
Coming soon

What is the role of allo-SCT for the treatment of MDS?

Alain Mina
Should we transplant TP53-mutated MDS patients?: No
Alain Mina National Cancer Institute, DC, WA, United States
Coming soon
Should we transplant TP53-mutated MDS patients?: Yes
Coming soon

Keynote talk  

Alan List
Clinical development of lenalidomide in LR-MDS a lesson in drug development
Alan List Precision BioSciences, Durham, NC, United States
Coming soon

What are the right endpoints for future MDS clinical trials?

Rami Komrokji
What are the right endpoints for lower-risk and higher-risk MDS trials?
Rami Komrokji Moffitt Cancer Center, Tampa, FL, United States
Coming soon
Industry perspective on drug approval for MDS
Coming soon
Nina Kim
FDA views on drug approval for MDS
Nina Kim U.S. Food & Drug Administration, Silver Spring, MD, United States
Coming soon
Statistical perspectives and trial designs for MDS
Coming soon
Andrew Brunner
Clinical trial reporting in MDS
Andrew Brunner Massachusetts General Hospital, Boston, MA, United States
Coming soon

Quo vadis MDS? Where do we go from here? Short perspectives on future plans for clinical trials from around the world (Part 1)

Steven Gore
CTEP views on use for novel agents in MDS
Steven Gore National Cancer Institute, Bethesda, MD, United States
Coming soon
Olatoyosi Odenike
Important US MDS trials
Olatoyosi Odenike Duchossois Center for Advanced Medicine, Chicago, IL, United States
Coming soon
Rena Buckstein
The Canadian plan for MDS trials
Rena Buckstein Sunnybrook Health Sciences Centre
Coming soon

Quo vadis MDS? Where do we go from here? Short perspectives on future plans for clinical trials from around the world (Part 2)

Bing Li
The Chinese plan for MDS trials
Bing Li Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
Coming soon
The Scandinavian plan for MDS trials
Coming soon
Ioannis Kotsianidis
The Greek plan for MDS trials
Ioannis Kotsianidis Thrace University, School of Medicine, Alexandroupolis, Greece
Coming soon
Lynette Chee
The Australian plan for MDS trials
Lynette Chee The Royal Melbourne Hospital & Peter MacCallum Cancer Centre, Melbourne, Australia
Coming soon

Novel targets in MDS

Hetty Carraway
What are the next promising targets for higher-risk MDS?
Hetty Carraway Cleveland Clinic, Cleveland, OH, United States
Coming soon
Elizabeth Griffiths
What are the next promising targets for lower-risk MDS?
Elizabeth Griffiths Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States
Coming soon
Valeria  Santini
Targeting the TGF pathway and inflammation in MDS
Valeria Santini University of Florence, Florence, Italy
Coming soon

How should we think about MRD in MDS?

Arjan van de Loosdrecht
Flow cytometry for MRD in MDS
Arjan van de Loosdrecht Amsterdam UMC, Amsterdam, Netherlands
Coming soon
Andrew Brunner
Clinical application and limitations of measurable residual disease in MDS
Andrew Brunner Massachusetts General Hospital, Boston, MA, United States
Coming soon

The iwMDS/MPN 2026 meeting was supported by:

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