Elena Zamagni, MD, PhD, University of Bologna, Bologna, Italy, discusses the multiple options available for the detection of bone and bone marrow lesions, from whole-body CT, PET/CT, and MRI. Dr Zamagni mentions the International Myeloma Working Group recommendations on imaging in multiple myeloma (MM). This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).