Yes, I think that in the solitary plasmacytoma really two things are game-changers. Imaging, that’s really the place where you have to implement at maximum your resources to provide good imaging because you are really preventing major errors, dramatic errors. So there is a place for diffusion-weighted whole body MRI or PET-CT, because if you’re mistaking from the beginning, you’re doing a tremendous mistake...
Yes, I think that in the solitary plasmacytoma really two things are game-changers. Imaging, that’s really the place where you have to implement at maximum your resources to provide good imaging because you are really preventing major errors, dramatic errors. So there is a place for diffusion-weighted whole body MRI or PET-CT, because if you’re mistaking from the beginning, you’re doing a tremendous mistake. So this is one. And for sure, the bone marrow is also important, despite the fact that if you find an MGUS profile in the bone marrow, maybe it’s a little bit more tricky whether to stick to the treatment of solitary plasmacytoma or to go for a more diffuse treatment. So it’s important to have correct follow-up for sure. It’s important always, also in multiple myeloma, but I think that in solitary plasmacytoma it’s absolutely necessary and yes the first recommendation is radiotherapy I think that we clarify that even for patients who receive surgery maybe for diagnostic reasons you still have to provide radiotherapy so I think that now with these guidelines it’s a little bit more easy for maybe physicians with less experience to correctly manage these patients.
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