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ASH 2022 | Retrospective analysis on the role of allogeneic transplantation in 3L B-NHL in the CAR-T era

Anna Sureda, MD, PhD, Catalan Institute of Oncology, Duran I Reynals Hospital, Barcelona, Spain discusses the results of a retrospective analysis that evaluated the role of allogeneic stem cell transplantation (alloSCT) for the third-line treatment of diffuse large B-cell lymphoma (DLBCL) in the CAR-T therapy era. The study reported similar long-term survival outcomes in both groups despite the fact that patients in the CAR-T group had poorer prognostic features. Whilst CAR-T is the preferred third-line option for DLBCL, alloSCT remains a suitable option for a select subset of patients. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

Takeda: Consultancy, Honoraria, Research Funding, Speakers Bureau; BMS/Celgene: Consultancy, Honoraria, Research Funding; MSD: Consultancy, Honoraria; Kite: Consultancy, Honoraria; Novartis: Consultancy, Honoraria; Jannsen: Consultancy, Honoraria; Sanofi: Consultancy, Honoraria; GenMab: Consultancy, Honoraria; Pierre Fabre: Consultancy, Honoraria; Astra Zeneca: Consultancy, Honoraria.