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COSTEM 2022 | The future of CAR-T therapy in the management of DLBCL

Anna Sureda, MD, PhD, Catalan Institute of Oncology, Duran I Reynals Hospital, Barcelona, Spain, comments on the current role of CAR-T therapy in the treatment of relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL). Whilst autologous stem cell transplantation (ASCT) has been the standard of care, multiple trials including the ZUMA-7 (NCT03391466) and TRANSFORM trials (NCT03575351) assessing axicabtagene ciloleucel (axi-cel) and lisocabtagene maraleucel (liso-cel) respectively have put CAR-Ts on the forefront of DLBCL treatment. This interview took place at the 7th Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) in Berlin, Germany.

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