Moritz Binder, MD, MPH, Mayo Clinic, Rochester, MN, discusses the role of bone marrow stromal cells in high-risk multiple myeloma. Dr Binder explains that a recent study has shown that stromal cells remodel the epigenome upon interaction with multiple myeloma cells and induce dynamic gene expression changes related to high-risk features. Targeting these genes might constitute a promising therapeutic strategy. This interview took place at the 19th International Myeloma Society Meeting (IMS) held in Los Angeles, CA.
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