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iwAL 2026 | Optimizing allogeneic transplantation through prospective randomized trials in AML

Charles Craddock, CBE, FRCP(UK), FRCPath, DPhil, FMedSci, University of Birmingham, Birmingham, UK, discusses the UK IMPACT transplant trials network and the importance of prospective randomized studies in optimizing allogeneic stem cell transplantation for acute myeloid leukemia (AML). He highlights the network’s successful recruitment of more than 1,500 patients to trials evaluating strategies to reduce transplant-related toxicity and relapse, including approaches to graft-versus-host disease and conditioning. This interview took place at the 8th International Workshop on Acute Leukemias (iwAL 2026), held in Boston, MA.

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