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iwMDS 2025 | Advances made in MDS classification and risk stratification: ongoing work & future perspectives
In this discussion, Uma Borate, MD, The Ohio State University, Columbus, OH, Luca Lanino, MD, PhD, Yale University, New Haven, CT, Robert Hasserjian, MD, Massachusetts General Hospital, Boston, MA, and Zoey Xie, MD, MS, Moffitt Cancer Center, Tampa, FL, discuss updates in the classification and risk stratification of myelodysplastic syndromes (MDS). They first discuss changes that have been made in disease prognostication, highlighting the increasing importance of genetic features in defining disease groups. The experts also comment on the potential of using artificial intelligence (AI) to aid clinicians, and conclude by sharing insights into the precursor conditions clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS). This discussion took place at the 3rd International Workshop on Myelodysplastic Syndromes & Myeloproliferative Neoplasms (iwMDS & iwMPN) 2025, held in Lisbon, Portugal.
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