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SOHO 2023 | Considerations for risk-adapted therapy in lower-risk MDS

Robert Hasserjian, MD, Massachusetts General Hospital, Boston, MA, discusses the selection of patients with lower-risk myelodysplastic syndromes (LR-MDS) based on genetics and the Molecular International Prognostic Scoring System (IPSS-M), for a risk-adapted therapy approach. Dr Hasserjian comments on the prevalence of SF3B1 mutation in a large proportion of patients with LR-MDS, and further addresses the importance of using prognostic tools such as the IPSS-M to define the risk of MDS in patients with wild-type SF3B1. This interview took place at the Eleventh Annual Meeting of the Society of Hematologic Oncology (SOHO 2023) held in Houston, TX.

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