Charles Craddock, CBE, FRCP (UK), FRCPath, DPhil, University of Birmingham, Birmingham, UK, talks on the efficacy of myeloablative conditioning (MAC) and reduced-intensity conditioning (RIC) prior to transplant for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).