Anna Sureda, MD, PhD, of the Catalan Institute of Oncology, Barcelona, Spain, discusses the use of post-transplant cyclophosphamide. Cyclophosphamide is given after allogeneic stem cell transplantation as a graft-versus-host disease (GvHD) prophylaxis platform as it is very effective in the context of haploidentical transplants. For this reason, it has made the process of allogeneic stem cell transplantation accessible to almost all patients. Dr Sureda predicts that in the future, cyclophosphamide will be used more broadly. This interview took place at the 4th Annual Meeting of the International Academy for Clinical Hematology (IACH), which took place virtually in 2021.