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ASH 2023 | Outcomes for patients with multiple myeloma who have had first-line monoclonal antibody exposure

Luciano Costa, MD, PhD, UAB School of Medicine, Birmingham, AL, discusses a study exploring the outcomes of patients with multiple myeloma (MM) who relapse after quadruplet therapy with a monoclonal antibody followed by autologous stem cell transplantation (autoSCT). Early progression leads to poorer survival, while later progression shows improved outcomes but still shorter progression-free survival (PFS) compared to those without prior monoclonal antibody exposure. This underscores the importance of considering previous exposure and timely access to novel therapies. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Adaptive biotechnologies: Consultancy, Honoraria; Amgen: Consultancy, Honoraria, Research Funding; Genentech: Research Funding; AbbVie: Honoraria, Research Funding; Janssen: Consultancy, Honoraria, Research Funding; Pfizer: Consultancy, Honoraria; BMS: Consultancy, Honoraria, Research Funding.