Thomas Martin, MD, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, shares an update on health-related quality-of-life (HRQoL) data from the Phase Ib/II CARTITUDE-1 study (NCT03548207) investigating ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR) T-cell therapy targeting B-cell maturation antigen (BCMA), in patients with relapsed/refractory multiple myeloma. Analysis found that patients with relapsed/refractory multiple myeloma showed rapid and clinically meaningful improvements in HRQoL after receiving a cilta-cel infusion. It was also found that HRQoL improved with increased depth of response. This interview took place during the 2021 European Myeloma Network (EMN) congress.