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ASH 2023 | A cost per responder analysis of cilta-cel vs physician’s choice in lenalidomide-refractory MM

Doris Hansen, MD, Moffitt Cancer Center, Tampa, FL, presents the findings of a cost per responder (CPR) analysis of patients with relapsed and lenalidomide-refractory multiple myeloma (MM) enrolled in the CARTITUDE-4 trial (NCT04181827), comparing ciltacabtagene autoleucel (cilta-cel) to pomalidomide, bortezomib and dexamethasone (PVd) or daratumumab, pomalidomide and dexamethasone (DPd). This analysis highlighted that the costs per complete responder and per month in progression-free survival (PFS) were substantially lower when treating patients with cilta-cel; an important factor for physicians to consider when choosing between cilta-cel, PVd, or DPd. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Consultancy: Bristol Myers Squibb, Karyopharm, Janssen, Pfizer; Membership on an entity’s Board of Directors or advisory committees: Bristol Myers Squibb, Pfizer; Research Funding: Bristol Myers Squibb, Karyopharm, International Myeloma Society Young Investigator Award, Pentecost Family Myeloma Research Center; Honoraria: OncLive, Survivorship