IMW 2021 | IMW highlights: the myeloma transcriptome
Jill Corre, PharmD, PhD, of L’Institut Universitaire du Cancer de Toulouse-Oncopole, Centre Hospitalier Universitaire, Toulouse, France, shares highlights from her presentation on the myeloma transcriptome at IMW 2021. Dr Corre outlines the seven sub-molecular groups that myeloma can be divided into according to cyclin D dysregulation and other clinical and biological features. Dr Corre also explains that gene expression profiling can be used to predict survival outcomes and disease aggression, which can help inform treatment decisions. Additionally, Dr Corre talks on advances in sequencing techniques, such as next generation sequencing (NGS) and high throughput sequencing, allowing for the identification of important modifiers of the transcriptome which may ordinarily be missed when looking at global transcript expression. This interview took place during the 18th International Myeloma Workshop (IMW 2021) congress.
