Saad Usmani, MD, MBBS, MBA, of the Levine Cancer Institute/Carolinas HealthCare System, Charlotte, NC, talks on the role of measurable residual disease (MRD) in the management of patients with multiple myeloma and how MRD can be incorporated into clinical practice. Dr Usmani also talks on the future role of MRD, commenting on the potential use of MRD-driven adaptive strategies in the future. This interview took place during the 18th International Myeloma Workshop (IMW 2021) congress.