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ASH 2023 | Cilta-cel in earlier lines of therapy for R/R multiple myeloma

Roberto Mina, MD, University of Turin, Turin, Italy, briefly discusses the use of ciltacabtagene autoleucel (cilta-cel) in patients with relapsed/refractory (R/R) multiple myeloma (MM), referencing the CARTITUDE-1 (NCT03548207) and CARTITUDE-4 (NCT04181827) trials. CARTITUDE-1 indicated that this CAR T-cell therapy is efficacious in heavily pre-treated patients, and CARTITUDE-4 aimed to investigate whether the same benefits to survival outcomes are seen when administering cilta-cel in earlier lines of treatment. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Consultancy: Janssen, Sanofi, Takeda
Honoraria: Janssen, Pfizer, Amgen, Takeda, Celgene
Membership on Board of Directors or advisory committee: Janssen, Bristol Myers Squibb, Amgen, Takeda, Celgene