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ASH 2020 | Anti-BCMA CAR T-cell therapy in myeloma: updates from ASH 2020

Saad Usmani, MD, MBBS, MBA, Levine Cancer Institute, Charlotte, NC, provides an overview of the latest trial updates presented at ASH 2020 for several B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell therapies for multiple myeloma. He also discusses the promise of off-the-shelf allogeneic CAR T-cell therapies but considers the potential obstacles related to this treatment modality. This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.

Disclosures

Saad Usmani, MD, MBBS, MBA, has received research funding from Amgen, Array Biopharma, BMS, Celgene, GSK, Janssen, Merck, Pharmacyclics, Sanofi, Seattle Genetics, SkylineDX and Takeda; has received consulting fees from Abbvie, Amgen, BMS, Celgene, GSK, Genentech/Roche, Janssen, Karyopharm, Merck, Oncopeptides, Sanofi, Seattle Genetics, SkylineDx and Takeda; and has received speaking fees from Celgene, Janssen, Sanofi and Takeda.

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