Jill Corre, PharmD, PhD, The Cancer University Institute of Toulouse Oncopole (IUCT), Toulouse, France, briefly explains what steps need to be taken to get closer to achieving a cure in multiple myeloma, drawing focus on the need to improve methods of detecting high-risk patients at diagnosis and prevent subclonal evolution so that patients can be treated earlier. This interview took place at the 8th World Congress on Controversies in Multiple Myeloma (COMy) 2022, held in Paris, France.