Ola Landgren, MD, PhD, from the Memorial Sloan Kettering Cancer Center, New York, NY, explains that minimal residual disease (MRD) monitoring for multiple myeloma (MM) is here to stay at the 2017 British Society for Haematology (BSH) Annual Scientific Meeting in Brighton, UK. He discusses ongoing work to improve and standardize MRD test technologies around the world, and how MRD assays can be used to test depth of response to new therapies and monitor patients to detect relapse early.