Amer Zeidan, MBBS, MHS, Yale University and Yale Cancer Center, New Haven, CT, discusses the comparative results of azacitidine and decitabine from a large prospective Phase III study in treatment-naive acute myeloid leukemia (AML) not eligible for intensive chemotherapy. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).