Ola Landgren, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, NY, discusses the use of daratumumab with carfilzomib, lenalidomide, and dexamethasone (dara-KRd) for the treatment of newly diagnosed multiple myeloma. Prof. Landgren goes on to highlight how the achievement of durable responses without the use of transplantation is important in light of the current COVID-19 pandemic that may impact immunosuppressed patients. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).