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SOHO 2026 | Key factors guiding CAR-T vs bispecific selection in FL: clinical and patient considerations

Juan Alderuccio, MD, Sylvester Comprehensive Cancer Center, Miami, FL, discusses treatment selection between CAR T-cell therapy and bispecific antibodies for follicular lymphoma (FL), emphasizing the lack of randomized data favoring either approach. Dr Alderuccio highlights prior bendamustine exposure as a key consideration due to its potential impact on CAR-T efficacy, with patient preferences helping to guide treatment decisions. This interview took place at the 14th Annual Meeting of the Society of Hematologic Oncology (SOHO 2026) in Houston, TX.

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