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ICLE 2022 | Enhancing personalized therapeutic cancer vaccine development

Chiara Bonini, MD, Vita-Salute San Raffaele University & IRCCS San Raffaele Institute, Milan, Italy, describes the current landscape of personalized therapeutic cancer vaccine development. She explains that early cancer vaccines had poor efficiency and did not elicit responses in large enough frequencies of patients, however, the combination of adoptive T cell therapy technology with tumor vaccination approaches allows lymphocytes to be sustained in patients for longer and offers the potential to have a clinical impact in a larger patient population. This interview took place at the International Conference on Lymphocyte Engineering (ICLE) 2022.