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IMS 2026 | Functional cure with earlier cilta-cel treatment in relapsed multiple myeloma

Hermann Einsele, MD, FRCP, University of Würzburg, Würzburg, Germany, discusses emerging evidence for functional cure in patients with relapsed multiple myeloma treated with ciltacabtagene autoleucel (cilta-cel). He highlights the International Myeloma Society (IMS) definition of functional cure, incorporating sustained progression-free survival (PFS) without treatment, confirmed measurable residual disease (MRD) negativity and negative imaging, and notes increasing rates of patients meeting these criteria with earlier use of cilta-cel. This interview took place at the 23rd International Myeloma Society (IMS) Annual Meeting in Glasgow, UK.

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