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ASH 2025 | Multimodal assessment of CMML with extramedullary involvement reveals RAS pathway activation

Sanam Loghavi, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, discusses the findings of a study in which a multimodal assessment of chronic myelomonocytic leukemia (CMML) cases with extramedullary involvement was conducted. Dr Loghavi highlights that extramedullary disease in CMML was associated with RAS pathway activation, epithelial-mesenchymal transition, and diverse phenotypes. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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