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ASH 2023 | Real-world outcomes of ide-cel in heavily pre-treated R/R MM

Surbhi Sidana, MD, Stanford University, Stanford, CA, discusses the real-world outcomes of over 800 patients with relapsed/refractory (R/R) multiple myeloma who have been treated with the CAR T-cell therapy idecabtagene vicleucel (ide-cel). These patients were heavily pre-treated (a median of seven prior lines of therapy) and many had high-risk cytogenetics which would have made them ineligible for the KarMMa-3 clinical trial (NCT03651128). With a median follow-up of around 12 months, safety and efficacy outcomes have been found to be comparable to those observed in KarMMa-3. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Consultancy: Magenta Therapeutics, BMS, Janssen, Sanofi, Oncopeptides, Takeda, Pfizer
Research Funding: Magenta Therapeutics, BMS, Allogene, Janssen, Novartis