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ASH 2023 | Ide-cel therapy for multiple myeloma with renal impairment

Surbhi Sidana, MD, Stanford University, Stanford, CA, presents findings from a retrospective study comparing outcomes of idecabtagene vicleucel (ide-cel) therapy in multiple myeloma patients with renal impairments versus those without. The study reveals comparable safety profiles between the two groups, with an initial rise in cytopenias in renal-impaired patients, which equalized by day 90 of treatment. Additionally, the efficacy of ide-cel remains consistent, positioning this CAR-T therapy as a safe and effective option for MM patients with renal impairments. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Consultancy: Magenta Therapeutics, BMS, Janssen, Sanofi, Oncopeptides, Takeda, Pfizer
Research Funding: Magenta Therapeutics, BMS, Allogene, Janssen, Novartis