In this video, Claudio Cerchione, MD, PhD, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, shares some insights into the promise of CAR-T therapy for the future treatment of multiple myeloma, and the need for CAR-T therapies to be approved in European countries. Dr Cerchione also highlights the importance of defining the best sequencing for CAR-T therapy and bispecific antibodies, as well as the importance of redefining risk in patients. This interview took place at the 8th World Congress on Controversies in Multiple Myeloma (COMy) 2022, held in Paris, France.