Richard Rosenquist, MD, PhD, Karolinska Institute, Stockholm, Sweden, discusses how molecular analysis is now used more frequently for patients with chronic lymphocytic leukemia (CLL) and describes the three most common tests performed – FISH analysis, TP53 sequencing and IGHV gene mutation status. Dr Rosenquist also details how TP53 mutations can emerge abruptly, explaining that these types of molecular tests should be done before treatment initiation and at relapse. This interview took place at the 2022 European Research Initiative on CLL (ERIC) Meeting.
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