In this video, Paul Richardson, MD, Dana-Farber Cancer Institute, Boston, MA, shares some insights into the long-term follow-up of the TOURMALINE-MM1 trial (NCT01564537) evaluating the safety and efficacy of ixazomib, lenalidomide, and dexamethasone for the treatment of relapsed/refractory (R/R) myeloma. Dr Richardson comments on some results from this trial and further explains the importance of interpreting overall survival data appropriately. This interview took place at the 8th World Congress on Controversies in Multiple Myeloma (COMy) 2022, held in Paris, France.