Siddhartha Jaiswal, MD, PhD, of Stanford University, Stanford, CA, discusses the interesting new field of clonal hematopoiesis of indeterminate potential (CHIP) and its role in leukemogenesis. Dr Jaiswal covers who this affects, what genes are most commonly mutated in the process, its effect on disease predisposition, and the potential to target it in the future. This interview took place at the International Symposium on Acute Leukemias (ISAL) 2019, held in Munich, Germany.