The Jaiswal lab at Stanford University, Stanford, CA, has lots of exciting ongoing research, focusing on somatic mutations and how they contribute to the development of cancer and other age-associated diseases. Here, Siddhartha Jaiswal, MD, PhD, discusses some of this work, and gives us an update on an upcoming paper. This interview took place at the International Symposium on Acute Leukemias (ISAL) 2019, held in Munich, Germany.