Barbara Eichhorst, MD, from the University Hospital of Cologne, Cologne, Germany, discusses the data on the CLL14 trial (NCT02242942) that were presented at the European Hematology Association (EHA) 2019, held in Amsterdam, Netherlands. This was a trial of fixed-duration venetoclax and obinutuzumab, and the results presented demonstrated the impact of this treatment on PFS and MRD status in previously untreated chronic lympocytic leukemia (CLL).