Irene Ghobrial, MD, Dana-Farber Cancer Institute, Boston, MA, discusses the direct-to-patient Multiple Myeloma Research Foundation (MMRF) CureCloud Research Initiative. This study has developed a clinical-grade next-generation liquid biopsy sequencing platform, which allows for minimally invasive monitoring of multiple myeloma from home. Genomic reports are provided to the patients through the CureCloud platform and can be used for clinical care and trial identification. This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.