ASH 2022 | Results from Phase I study of alnuctamab administered intravenously & subcutaneously in R/R myeloma
Sandy Wong, MD, University of California San Francisco, San Francisco, CA, gives an update on a Phase I trial evaluating intravenous (IV) or subcutaneous alnuctamab in patients with relapsed/refractory (R/R) multiple myeloma (NCT03486067). Whilst IV alnuctamab was associated with high-grade cytokine release syndrome (CRS), the trial found that administering alnuctamab subcutaneously led to better efficacy and an improved safety profile. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.
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Disclosures
Catalent Biologics: Consultancy; Bristol Myers Squibb: Research Funding; Caelum: Research Funding; Genentech: Research Funding; Patient Discovery: Research Funding; Fortis: Research Funding; GSK: Research Funding; Janssen: Research Funding; Sanofi: Membership on an entity’s Board of Directors or advisory committees; Dren Bioscience: Consultancy.
