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EHA 2023 | MajesTEC-2 update: teclistamab plus lenalidomide in R/R multiple myeloma

Carlyn Tan, MD, Memorial Sloan Kettering Cancer Center, New York City, NY, summarizes the key findings of the Phase Ib MajesTEC-2 study (NCT04722146) which investigated the combination of teclistamab with standard of care therapies, including lenalidomide, for patients with relapsed/refractory (R/R) triple-class exposed (TCE) multiple myeloma. Dr Tan highlights the favorable safety profile and efficacy of the teclistamab and lenalidomide combination, with toxicity rates consistent with the MajesTEC-1 (NCT04557098) trial that evaluated teclistamab alone. This interview took place at the 28th Congress of the European Hematology Association (EHA) 2023 in Frankfurt, Germany.

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Disclosures

Janssen – research funding, advisory board
Sanofi – advisory board
Takeda – research funding