Andrew Davies, BSc, BM, MRCP, PhD, of the University of Southampton, Southampton, UK, discusses the role of mediastinal radiotherapy after rituximab-containing chemotherapy regimens in patients with newly diagnosed primary mediastinal large B-cell lymphoma as evaluated in the IELSG 37 study (NCT01599559). This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).