BSH 2023 | REMoDL-B: bortezomib + R-CHOP versus R-CHOP in patients with DLBCL
Andrew Davies, MRCP, PhD, University of Southampton, Southampton, UK, discusses results from a long-term follow-up of the Phase III REMoDL-B trial (NCT01324596), which investigated whether there was any benefit to adding bortezomib to R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) in patients with diffuse large B-cell lymphoma (DLBCL). At a median follow-up of five years, improved progression-free and overall survival (PFS; OS) were observed in patients with activated B-Cell (ABC) lymphoma, suggesting that the addition of bortezomib may benefit patients with specific molecular subtypes of DLBCL. This interview took place at the 63rd Annual Scientific Meeting of the British Society for Haematology (BSH) 2023, held in Birmingham, UK.
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