The high-risk abnormality del(17p) has a negative prognostic impact in patients with multiple myeloma. In this video, Morie Gertz, MD, MACP, Mayo Clinic College of Medicine, Rochester, MN, outlines the outcomes of multiple myeloma patients with Del 17p undergoing autologous stem cell transplantation. This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.