Maria-Victoria Mateos, MD, PhD, University Hospital of Salamanca, Salamanca, Spain, discusses the Phase III COLUMBA (NCT03277105) study evaluating subcutaneous intravenous (IV) daratumumab in relapsed/refractory (R/R) multiple myeloma patients, specifically discussed is the results of the bodyweight subgroup analysis. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).