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IMS 2026 | Treatment strategies without access to BCMA- or GPRC5D-directed therapies

Martin Kaiser, MD, FRCP, FRCPath, The Royal Marsden NHS Foundation Trust, London, UK, discusses treatment strategies for patients with multiple myeloma at first relapse who do not have access to newer BCMA- or GPRC5D-directed therapies. He highlights established antibody, immunomodulatory drug and proteasome inhibitor-based combinations that can provide durable responses, while emphasizing the importance of preserving quality of life and avoiding cross-resistance with therapies that may become available in subsequent lines. This interview took place at the 23rd International Myeloma Society (IMS) Annual Meeting in Glasgow, UK.

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