Paul Richardson, MD, of the Dana-Farber Cancer Institute, Boston, MA, discusses ENDURANCE (NCT01863550), which investigated the use of bortezomib, lenalidomide, and dexamethasone (RVD) compared to carfilzomib, lenalidomide, and dexamethasone (KrD) in newly-diagnosed multiple myeloma. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).