Kwee Yong, PhD, FRCP, FRCPath, University College London, London, UK, briefly highlights some of the exciting topics to be discussed in the field of myeloma at EHA 2022, including updates in immunotherapies and treatment approaches, and clinical trial data. This interview took place at the 8th World Congress on Controversies in Multiple Myeloma (COMy) 2022, held in Paris, France.