iwCAR-T 2023 | Lymphoma CAR and bispecific updates
In this captivating session chaired by Loretta Nastoupil, MD University of Texas MD Anderson Center, Houston, TX, Mazyar Shadman, MD Fred Hutchinson Cancer Research Center, Seattle, WA, and Tycel Phillips, MD, City of Hope, Duarte, CA, share the latest advances in CAR-T therapy and bispecific antibodies for lymphoma. The experts comment on CD22 CARs and third-generation CD20 CARs, and move on to the use of axicabtagene ciloleucel (axi-cel) in central nervous system (CNS) lymphoma and discuss real-world data on brexucabtagene autoleucel (brexu-cel) in mantle cell lymphoma (MCL). The experts then talk on strategies to overcome some of the limitations of autologous CAR-Ts, and discuss where bispecific antibodies may fit in the treatment landscape. This discussion took place at the 5th International Workshop on CAR-T (iwCAR-T) 2023 held in Scottsdale, AZ.
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