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IMS 2026 | Immune fitness and reconstitution after CAR T-cell therapy in multiple myeloma

Yi Lin, MD, PhD, Mayo Clinic, Rochester, MN, discusses immune fitness and immune reconstitution in multiple myeloma following CAR T-cell therapy and T-cell engagers. She highlights the potential impact of T-cell phenotypes and clonal expansion on treatment response and toxicity, while noting the need to translate high-dimensional immune profiling into clinically actionable tests. This interview took place at the 23rd International Myeloma Society (IMS) Annual Meeting in Glasgow, UK.

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