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BSH 2023 | Long-term risks associated with persistent isolated mild thrombocytopenia

Hanny Al-Samkari, MD, Massachusetts General Hospital, Boston, MA, discusses the long-term risks associated with persistent isolated mild thrombocytopenia (PIMT). Dr Al-Samkari explains that although PIMT diagnoses are common, there are currently no guidelines for addressing this condition. Dr Al-Samkari describes a recent study evaluating patients diagnosed with PIMT, showing that this patient group is at an elevated long-term risk of immune thrombocytopenia (ITP), myeloid or lymphoid hematologic neoplasms, severe bleeding episodes, and mortality compared to age- and sex-matched controls. Given these long-term risks, Dr Al-Samkari concludes by emphasizing the importance of developing clinical guidelines for patients upon a diagnosis of PIMT. This interview took place at the 63rd Annual Scientific Meeting of the British Society for Haematology (BSH) 2023, held in Birmingham, UK.

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Disclosures

Research funding to institution (Agios, Amgen, Novartis, Vaderis, Sobi); Consultancy (Agios, Novartis, Moderna, Rigel, argenx, Pharmacosmos, Sobi, Forma)