Geoffrey Shouse, DO, PhD, City of Hope, Duarte, CA, discusses the unmet needs in Richter’s transformation (RT), commenting on the possibility of using CAR T-cell therapy and bispecific antibodies in these patients. Dr Shouse highlights that novel therapeutic approaches and combinations will be needed to overcome the inhibitory immune microenvironment observed in RT. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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